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KMID : 0903520060490020097
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Journal of the Korean Society of Agricultural Chemistry and Biotechnology
2006 Volume.49 No. 2 p.97 ~ p.101
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Effects of Temperature and Relative Humidity on Fat Soluble Vitamin Contents in Commercial Vitamin Tablet
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Kim Dong-Sup
Choi Sung-Won
Park Suk-June
Kim Se-Kon
Baik Moo-Yeol
Lee Jin-Hee
Lee Kang-Pyo
Lee Jae-Hwang
Lee Dong-Un
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Abstract
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Effects of temperature and relative humidity on fat soluble vitamin contents in two commercial vitamin tablets (“Multivitamin Dandelion” and “vitamin E Yarrow”) were investigated. When they stored at different temperature (25, 35, and 45oC) with cap and stored at low relative humidity (11% RH) without cap, all fat soluble vitamins (vitamin A acetate, vitamin E acetate and vitamin E) were stable during 24 weeks of storage period. However, when they stored at high relative humidity (75% RH and 100% RH) without cap, vitamin A acetate and vitamin E acetate dramatically disintegrated at the early stage of storage. On the other hand, vitamin E gradually decreased during storage. Therefore, stability of some fat soluble vitamins, which exist as acetate form, was highly dependent on relative humidity rather than storage temperature. Water may act as a plasticizer and increased the mobility of molecules in vitamin tablet resulting in relatively fast disintegration of some fat soluble vitamins.
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KEYWORD
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fat-soluble vitamin, vitamin tablet, stability, temperature, relative humidity
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